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Vitamin D deficiency prevalent in patients with chronic liver disease

March 21st, 2011

We are aware of the prevalence of vitamin D deficiency all over the world, irrespective of the availability of sunshine. Vitamin D deficiency has been associated with a number of diseases like cancer, arthritis, asthma and cardiovascular diseases. There has been some evidence that suggest that vitamin D deficiency is also related to liver health.

In the recent past, a study was done to determine the prevalence of vitamin D deficiency in patients with chronic liver disease. The results found were surprising. Let’s see………

The investigators looked at the vitamin D levels of 118 patients with chronic liver disease (43 with hepatitis C cirrhosis, 57 with hepatitis C but no cirrhosis, 18 with non-hepatitis C-related cirrhosis). Severity of vitamin D deficiency was graded as mild (20-32 ng/ml), moderate (7-19 ng/ml) or severe (<7 ng/ml), normal being >32 ng/ml.

Most patients (92.4%) were found to have some degree of vitamin D deficiency. In the group with cirrhosis 16.3% had mild, 48.8% had moderate, and 30.2% had severe vitamin D deficiency. In the group with no cirrhosis, 22.8% had mild, 52.6% had moderate, and 14% had severe vitamin D deficiency. In the group of those with cirrhosis (but not hepatitis C) 38.9% had mild, 27.8% had moderate, and 27.8% had severe vitamin D deficiency. Patients with cirrhosis were more likely to have severe vitamin D deficiency (<7 ng/ml) than in those who did not have cirrhosis—29.5% versus 14.1%.

The study concluded that vitamin D is universally deficient among patients with chronic liver disease, and at least one-third of them suffer from severe vitamin D deficiency.

Vitamin D supplements are also effective in resolving vitamin D deficiency in people with chronic liver disease. Watch for our future posts to know more about this.

Our product Vitamin D10 is the best vitamin D supplement available over-the-counter that is physician & pharmacist formulated & approved. D10 provides Mother Nature’s intended daily dose of 10,000 IU of vitamin D3 in a once per day pulsed dose.

For more details, click here.

Source:
Digestive diseases and sciences

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