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Posts Tagged ‘Vitamin D IBD’

Why Crohn’s disease patients are vitamin D deficient?

January 25th, 2011

A recent study has shown that the vitamin D absorption is reduced in the quiescent Crohn’s disease, which is an inflammatory disease of the intestines, compared to the general population. The study also suggested that this may be the cause for their increased risk for vitamin D deficiency in such patients.

The study included 10 normal and 37 Crohn’s disease patients. A vitamin D bioavailability test was performed on all subjects at a baseline and 12 hours after a single 50,000 IU oral dose of vitamin D2 capsule.

The researchers found a 30 percent decrease in their ability to absorb vitamin D2 when compared to normal subjects. More than 70% of the patients were vitamin D-deficient or insufficient. They also found that the location of the disease, the type of the surgery, and receiving or not receiving surgery did not predict the ability to absorb vitamin D2.

The study concluded that since the ability to absorb vitamin D2 in such patients is unpredictable, vitamin D bioavailability test is the only method to determine the absorption efficiency. Vitamin D bioavailability test may help the patients of Crohn’s disease to determine their ability to process the nutrient.

This may guide your clinician in administering the appropriate therapeutic dose of vitamin D for treating vitamin D deficiency in patients with Crohn’s disease.

Vitamin D supplements available over the counter are of two types; vitamin D2 and vitamin D3. Most experts believe that Vitamin D3 is much more bioavailable as compared to vitamin D2. If you choose to take Vitamin D, supplements, make sure you are taking Vitamin D3 supplement.

Vitamin D10, is the best vitamin D3 supplement available over the counter that is Physician and pharmacist approved and provides 10,000 IUs of vitamin D3 in a natural pulsed form. Visit our products page to learn more about Vitamin D10.

Watch for our future blogs to learn more about the bioavailability of vitamin D3.

Source:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=21213288

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Vitamin D: Key to normal Gut functioning

July 11th, 2010

Vitamin D has been reported to have an immuno-modulatory role which helps to strengthen immunity and better manage auto-immune diseases like Inflammatory Bower Disease (IBD).  Now, a recent study by researchers at the University of Rochester suggests the possible mechanisms of action. The findings of this mice study suggest that vitamin D receptor is a key to control invading pathogenic bacteria like Salmonella by binding the inflammatory molecules and keeping it from activating other inflammatory molecules.

The researchers have further suggested that the study may also provide a new lead in understanding how microbes in the human digestive tract known as gut flora keep bad bacteria in check and how bacteria might play a role in the development of inflammatory bowel diseases such as Crohn’s disease or ulceractive colitis.

Interested in more details? Review our articles on the role of Vitamin D in strengthening immunity and how Vitamin D3 supplementation may help you improve IBD.

Source:
http://www.ncbi.nlm.nih.gov/pubmed/20566739
http://www.upi.com/Health_News/2010/07/08/Vitamin-D-Key-to-gut-functioning/UPI-79521278621244/

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